Modern Mac computers utilize M-Series ARM processors. Illustrator CS6 was compiled strictly for Intel (x86_64) processors. While Apple's Rosetta 2 translation layer handles many Intel apps, it cannot execute the 32-bit licensing modules embedded in CS6.
The barrier to running Illustrator CS6 on modern Apple hardware is much more severe:
The "updated patch" typically refers to the transition from the base 16.0.0 release to the final stable updates. The final version numbers differ based on your licensing type: Non-Subscription (Perpetual License): The final update is for Windows and for macOS. Subscription (Creative Cloud): The final version for CS6 reached for Windows and for macOS. Adobe Help Center Key Features of the 16.0.x Architecture Native 64-bit Support: