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| System | Possible Reactions | Frequency* | |--------|-------------------|------------| | | Local burning, itching, contact dermatitis, skin atrophy (with prolonged steroid use) | Mild‑to‑moderate; usually reversible after discontinuation | | Gastrointestinal (oral) | Nausea, diarrhea, abdominal pain | Mild, in ≤10 % of users | | Systemic (oral) | Tendonitis/tendon rupture, QT prolongation, CNS effects (headache, dizziness) – typical fluoro‑quinolone concerns | Rare; risk rises with >5 days use, concomitant steroids, or in elderly patients | | Allergic | Urticaria, angioedema | Very rare, but requires immediate medical attention |