An early, challenging look at Thirteen’s mysterious life and her fear of Huntington's disease.

House begins the season attempting to work alone, but after pestering from Cuddy and Wilson, he invites to compete for three open spots on his diagnostic team. This "Survivor-style" elimination process defines the first half of the season, with House assigning them numbers instead of learning their names. The New Team & Major Characters By mid-season, the permanent new team is finalized: Dr. Lawrence Kutner

Season 4 was a critical and commercial success. The show successfully weathered the departure of the original cast, proving the strength of the central character and the writing. Hugh Laurie received Primetime Emmy Award nominations for Outstanding Lead Actor in a Drama Series for his work in this season.

The fourth season of the popular American medical drama series, House MD, premiered on September 18, 2007, and concluded on May 19, 2008. Created by David Shore, the show revolves around the life of Dr. Gregory House, a misanthropic medical genius who leads a team of diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital (PPTH). In this article, we will delve into the intricacies of Season 4, exploring its plotlines, character developments, and the overall impact of the series.

House looked at her, then at Thirteen and Kutner. “She’s right. But she’s also just proven my point. You’re better together than apart.”

Amber interrupted. “They’re wrong about the timing. The liver failure isn’t from the shunt. He’s been taking high-dose ibuprofen for shin splints. Rhabdomyolysis from the race plus NSAIDs equals acute liver injury. That’s three diseases.”

A bottle episode where House must diagnose a patient (Mira Sorvino) stranded in the South Pole via webcam. With no team physically present, House is forced to talk to the patient directly, revealing a rare moment of vulnerability in his attempts to connect with someone without his physical presence.

After his original team (Chase, Cameron, and Foreman) departs, House holds a Darwinian trial to find replacements. Notable new candidates include Lawrence Kutner (Kal Penn), Chris Taub (Peter Jacobson), and the enigmatic "Thirteen" (Olivia Wilde). The Final Team: